Bleonix

 

• Generic Name: Bleomycin Sulfate

• Strength: 15 units per vial

• Dosage Form: Injection (powder for reconstitution)

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Product Description:

Bleonix Injection contains Bleomycin Sulfate, a cytotoxic antibiotic derived from Streptomyces verticillus. It is primarily used as an anticancer agent (antineoplastic).

Bleomycin works by causing breaks in DNA strands, inhibiting DNA synthesis, and leading to apoptosis (cell death), particularly in rapidly dividing cancer cells.

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Indications:

Bleonix (Bleomycin Sulfate) is commonly used in the treatment of:

• Hodgkin's lymphoma

• Non-Hodgkin's lymphoma

• Testicular cancer

• Squamous cell carcinomas (head, neck, cervix)

• Malignant pleural effusion (as sclerosing agent)

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Dosage:

• Typical Adult Dose:
  Varies depending on indication, body surface area, and treatment regimen.
  Example:

  • 10–20 units/m² IV/IM/subcutaneous, 1–2 times per week

  • Maximum cumulative dose: 400 units (due to risk of pulmonary toxicity)

Note: Dose must be individualized based on the type of cancer, treatment protocol, and patient condition. Always to be administered under specialist supervision.

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Warnings:

• Pulmonary toxicity is the most serious side effect.

• Monitor lung function regularly.

• Use with caution in elderly and those with preexisting lung conditions.