Dasanix

20 mg

50 mg

100 mg

• Generic Name: Dasatinib

• Description:
  Dasanix is a brand name for Dasatinib, a tyrosine kinase inhibitor used in the treatment of certain types of leukemia. It works by blocking the activity of abnormal proteins that signal cancer cells to grow. Specifically, Dasatinib inhibits the BCR-ABL kinase and other kinases involved in chronic myeloid leukemia (CML) and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL).

Key Indications:

• Chronic Myeloid Leukemia (CML) in chronic, accelerated, or blast phases

• Philadelphia chromosome-positive Acute Lymphoblastic Leukemia (Ph+ ALL)

Mechanism of Action:
Dasatinib binds to and inhibits the BCR-ABL kinase, preventing downstream signaling that promotes proliferation and survival of leukemia cells. It also targets other kinases like SRC family kinases, c-KIT, and PDGFR.

Dosage Forms:
Available in tablet form in various strengths, commonly 20 mg, 50 mg, 70 mg, 80 mg, 100 mg, and 140 mg.

Common Side Effects:
Myelosuppression (low blood cell counts), fluid retention, diarrhea, headache, rash, and fatigue.

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