Perfex Suspension

Brand Name - antihistamine

generic name - Fexofenadine Hydrochloride

Product Description

• Active Ingredient: Fexofenadine Hydrochloride (30 mg per 5 ml) .

• Therapeutic Class: Non-sedating H₁ antihistamine.

• Mechanism: Selectively blocks peripheral H₁ receptors to reduce allergy symptoms like sneezing, runny nose, and hives. It doesn't cross the blood-brain barrier, so it’s less likely to cause drowsiness. 

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✅ Indications

Suitable for:

• Seasonal allergic rhinitis (e.g., hay fever)

• Chronic idiopathic urticaria (hives)

It's approved for use in children aged 2 years and above (as an oral suspension) and adults.

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💊 Dosage & Administration

• Children (2–11 years): 30 mg (5 ml) twice daily (maximum 60 mg/day).

• Adults & older children: Usually managed with tablets—but if suspension is used off-label, similar dosing applies under medical guidance.

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⚠️ Interactions & Safety

• Increased fexofenadine levels with erythromycin or ketoconazole—though no serious cardiovascular impact.

• Reduced absorption if taken with antacids containing aluminum or magnesium; separate dosing by ~2 hours .

• Avoid fruit juices (like apple, orange, grapefruit) around dosing—they may reduce effectiveness.

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⚕️ Contraindications & Precautions

• Not to be used by individuals with hypersensitivity to fexofenadine or any ingredient.

• Renal impairment may require dose adjustment (e.g., once daily) .

• Pregnancy/Lactation: Limited human data; use only if benefits outweigh risks. Small amounts may pass into breastmilk .

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🤒 Side Effects

Common (generally mild):

• Headache, fatigue, dry mouth

• Occasional nausea, dizziness — with overdose, also possible drowsiness.

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📦 Storage & Packaging

• Packaged as a 50 ml bottle with 30 mg/5 ml suspension.

• Store in a cool, dry place, away from light and children.

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💡 Summary Table