Peritop 50 mg Tablet

50 mg

🧬 Generic Name:

Itopride Hydrochloride

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💊 Product Description:

Peritop 50 mg is an anti-gastric motility agent used to treat various gastrointestinal disorders. It functions by enhancing gastric motility and improving coordination between the stomach and duodenum. This is achieved through its dual action as a dopamine D2 receptor antagonist and an acetylcholinesterase inhibitor, which increases acetylcholine levels, promoting smoother digestion .

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✅ Indications:

Peritop is commonly prescribed for:

• Chronic gastritis

• Functional dyspepsia

• Gastroesophageal reflux disease (GERD)

• Upper abdominal discomfort, nausea, and bloating

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💊 Dosage and Administration:

• Dosage: 50 mg per tablet

• Typical regimen: One tablet taken three times daily

• Administration: To be taken before meals

• Adjustments: Dosage may be modified based on age, symptoms, or specific medical conditions.

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⚠️ Warnings and Precautions:

• Pregnancy and Breastfeeding: Safety during pregnancy has not been established; use only if benefits outweigh risks. Not recommended during breastfeeding due to limited data .

• Liver and Kidney Function: Caution is advised in patients with liver or kidney disorders; dose adjustments may be necessary .

• Drug Interactions: Concurrent use with anticholinergic drugs (e.g., scopolamine, tiquizium bromide) may reduce the effectiveness of Peritop.

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⚠️ Side Effects:

Possible side effects include:

• Headache

• Dizziness

• Fatigue

• Abdominal discomfort

• Dry mouth

• In rare cases, galactorrhea or gynecomastia 

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🛒 Availability:

Peritop 50 mg tablets are available in strips of 15 tablets. Pricing may vary; for instance, Arogga Online Pharmacy lists it at approximately ৳69.81 per strip .

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🧪 Mechanism of Action:

Itopride Hydrochloride enhances gastrointestinal motility by:

• Blocking dopamine D2 receptors, which increases acetylcholine release

• Inhibiting acetylcholinesterase, preventing the breakdown of acetylcholine
  These actions collectively improve gastric emptying and duodenal coordination