Topoxin

Product Name:

Topoxin Injection

Generic Name:

Etoposide

Description:

Topoxin Injection contains Etoposide, a topoisomerase II inhibitor that prevents cancer cells from dividing and growing by causing DNA strand breaks. It is used as part of combination chemotherapy regimens for the treatment of small cell lung cancer, testicular cancer, lymphomas, and other malignancies.

Composition:

Each vial contains Etoposide at specified strengths (commonly available in 100 mg/5 ml or 200 mg/10 ml, depending on the manufacturer).

• Excipients: Includes solvents like polysorbate 80, ethanol, and benzyl alcohol.

Therapeutic Class:

Antineoplastic Agent (Topoisomerase II Inhibitor)

Indications:

• Small cell lung cancer

• Testicular cancer

• Non-Hodgkin’s lymphoma

• Acute myeloid leukemia (AML)

• Ovarian cancer (off-label use)

• Other solid tumors (as recommended by oncologists)

Dosage & Administration:

• Route: Intravenous infusion

• Dosage: Varies depending on cancer type, body surface area (BSA), and patient’s condition. Typically administered in cycles, alone or with other chemotherapy agents.

Storage:

Store below 25°C. Protect from light.

Warnings & Precautions:

• Risk of bone marrow suppression, infections, and allergic reactions.

• Should be administered under the supervision of experienced oncology healthcare professionals.

• Not recommended during pregnancy or breastfeeding unless clearly needed.

Side Effects:

• Bone marrow suppression (neutropenia, anemia, thrombocytopenia)

• Nausea, vomiting

• Hair loss (alopecia)

• Fatigue

• Hypotension during infusion

• Allergic reactions