cellular senescence
Senescent Cells and Kidney Disease: Is Cellular Aging the New Frontier?
Cellular senescence — the accumulation of damaged, permanently arrested cells that drive inflammation and fibrosis — is emerging as a key mechanism in CKD progression. Early clinical trials and preclinical data on senolytic compounds, including quercetin, fisetin, and dasatinib, suggest that targeting these cells may one day become a standard part of kidney disease management.
